Qin Li
Lieue University, ChinaPresentation Title:
High fat-induced the upregulation of LOX-1 in RF/6A cells under high glucose condition
Abstract
Diabetes mellitus (DM) is one of the most common metabolic diseases. Epidemiological investigations in recent years have revealed that Uyghurs living in Xinjiang have the highest prevalence of early DM. Diabetic retinopathy (DR), a common ocular complication of DM, might lead to the incidence of blindness in developed countries. We found that a certain concentration of ox-LDL blocks high-glucose-induced retinal vascular endothelial injury by inhibiting the upregulation of ICAM-1 due to a high-glucose environment. Dyslipidemia may play an important role in the development of diabetic retinopathy, emphasizing the importance of active regulation of blood lipids in diabetic retinopathy therapy.
Biography
Qin Li has completed her master’s degree at the age of 26 years from Xinjiang medical university, China. She worked in the Ophthalmology Department of the First Affiliated Hospital of Xinjiang Medical University for ten years, China. She has certain experience in the diagnosis and treatment of diabetic retinopathy.
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