Abimbola Lawal
Olabisi Onabanjo University Teaching Hospital, NigeriaPresentation Title:
CA19-9 and Diabetes Mellitus: Beyond cancer, what else do we need to know?
Abstract
Recent literature have highlighted the role of β-cell cellular dysfunction in the pathogenesis of hyperglycaemia in diabetes. Type 2 diabetes mellitus has been recognized as an inflammatory disease. Likewise glucotoxicity and increased adiposity induces oxidative stress and inflammatory cytokines leading to cellular damage and apoptosis in beta cells. Serum CA19-9 has been noted to be a marker of pancreatic tissue damage.
Serum CA19-9 which has been used traditionally as a screening tool for pancreatic cancer has also been found to be raised in other non-malignant diseases including diabetes mellitus.
Several studies have recognised that patients with poorly controlled diabetes have elevated serum levels of CA19-9 in the absence of gastrointestinal malignancies and this elevation is associated with metabolic control, pancreatic cell dysfunction and insulin resistance.
Biography
Abimbola O. Lawal completed his fellowship training in the field of Endocrinology, Diabetology and Metabolism in April 2022. He obtained two College awards from the WACP college. He is currently a consultant Endocrinologist/Physician at the Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria, where he trains medical students, interns and residents in the field of medicine and Endocrinology. His publications are available on Research Gate with RI score of 15.6 and h-index of 1. He has also served as a peer reviewer.
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